Overview

  • Product nameAnti-CHN 1 antibody
    See all CHN 1 primary antibodies
  • Description
    Mouse monoclonal to CHN 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 91-201 of Human CHN 1

Properties

Applications

Our Abpromise guarantee covers the use of ab54610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionGTPase-activating protein for p21-rac and a phorbol ester receptor. May play an important role in neuronal signal-transduction mechanisms.
    • Tissue specificityIn neurons in brain regions that are involved in learning and memory processes.
    • Involvement in diseaseDefects in CHN1 are the cause of Duane retraction syndrome type 2 (DURS2) [MIM:604356]. Duane retraction syndrome is a congenital eye movement disorder characterized by a failure of cranial nerve VI (the abducens nerve) to develop normally, resulting in restriction or absence of abduction, adduction, or both, and narrowing of the palpebral fissure and retraction of the globe on attempted adduction. Undiagnosed in children, it can lead to amblyopia, a permanent uncorrectable loss of vision.
    • Sequence similaritiesContains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 Rho-GAP domain.
      Contains 1 SH2 domain.
    • Developmental stageIncreases in amount during brain development coincident with synaptogenesis.
    • Information by UniProt
    • Database links
    • Alternative names
      • A-chimaerin antibody
      • Alpha-chimerin antibody
      • ARHGAP2 antibody
      • CHIN_HUMAN antibody
      • CHN antibody
      • Chn1 antibody
      • N chimaerin antibody
      • N chimerin antibody
      • N-chimaerin antibody
      • N-chimerin antibody
      • NC antibody
      • Rho GTPase-activating protein 2 antibody
      • RHOGAP2 antibody
      see all

    Anti-CHN 1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab54610 CHN 1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-CHN 1 antibody (ab54610)

    ab54610 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"