Anti-CHORDC1 antibody (ab106594)
Key features and details
- Rabbit polyclonal to CHORDC1
- Suitable for: ICC/IF, WB, ICC
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CHORDC1 antibody -
Description
Rabbit polyclonal to CHORDC1 -
Host species
Rabbit -
Specificity
At least two isoforms of CHORDC1 are known to exist; ab106594 will recognize both isoforms. -
Tested applications
Suitable for: ICC/IF, WB, ICCmore details -
Species reactivity
Reacts with: Human -
Immunogen
21 amino acid peptide from near the N terminus of Human CHORDC1 (NP_036256).
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Positive control
- 293 cells and cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Affinity chromatography purified via peptide column -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106594 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use a concentration of 20 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.
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ICC |
Use a concentration of 2.5 µg/ml.
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Notes |
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ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa. |
ICC
Use a concentration of 2.5 µg/ml. |
Target
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Function
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis. -
Tissue specificity
Underexpressed in many breast and lung cancers. -
Sequence similarities
Contains 2 CHORD domains.
Contains 1 CS domain. - Information by UniProt
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Database links
- Entrez Gene: 26973 Human
- Omim: 604353 Human
- SwissProt: Q9UHD1 Human
- Unigene: 22857 Human
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Alternative names
- CHORD containing protein 1 antibody
- Chord domain containing protein 1 antibody
- CHORD domain-containing protein 1 antibody
see all
Images
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Lane 1 : Anti-CHORDC1 antibody (ab106594) at 1 µg/ml
Lane 2 : Anti-CHORDC1 antibody (ab106594) at 2 µg/ml
All lanes : 293 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 37 kDa -
Immunofluorescence of CHORDC1 in 293 cells with ab106594 at 20 ?g/mL.
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ab106594 at 2.5 µg/ml detecting CHORDC1 in 293 cells by Immunocytochemistry.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab106594 has not yet been referenced specifically in any publications.