Overview

  • Product name
  • Description
    Rabbit polyclonal to CHORDC1
  • Specificity
    At least two isoforms of CHORDC1 are known to exist; ab106594 will recognize both isoforms.
  • Tested applications
    Suitable for: ICC/IF, WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    21 amino acid peptide from near the N terminus of Human CHORDC1 (NP_036256).

  • Positive control
    • 293 cells and cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Affinity chromatography purified via peptide column
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106594 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.
ICC Use a concentration of 2.5 µg/ml.

Target

  • Function
    Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
  • Tissue specificity
    Underexpressed in many breast and lung cancers.
  • Sequence similarities
    Contains 2 CHORD domains.
    Contains 1 CS domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • CHORD containing protein 1 antibody
    • Chord domain containing protein 1 antibody
    • CHORD domain-containing protein 1 antibody
    • CHORD-containing protein 1 antibody
    • CHORDC1 antibody
    • CHP-1 antibody
    • CHP1 antibody
    • CHRD1_HUMAN antibody
    • Cysteine and histidine rich domain (CHORD) containing 1 antibody
    • Cysteine and histidine rich domain (CHORD) containing, zinc binding protein 1 antibody
    • Cysteine and histidine rich domain containing 1 antibody
    • Cysteine and histidine rich domain containing zinc binding protein 1 antibody
    • Cysteine and histidine-rich domain-containing protein 1 antibody
    • FLJ37289 antibody
    • Protein morgana antibody
    see all

Images

  • Immunofluorescence of CHORDC1 in 293 cells with ab106594 at 20 ?g/mL.
  • Lane 1 : Anti-CHORDC1 antibody (ab106594) at 1 µg/ml
    Lane 2 : Anti-CHORDC1 antibody (ab106594) at 2 µg/ml

    Lane 1 : 293 cell lysate
    Lane 2 : 293 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 37 kDa
  • ab106594 at 2.5 µg/ml detecting CHORDC1 in 293 cells by Immunocytochemistry.

References

ab106594 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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