Anti-Chordin antibody - N-terminal (ab80146)

Overview

  • Product name
    Anti-Chordin antibody - N-terminal
    See all Chordin primary antibodies
  • Description
    Rabbit polyclonal to Chordin - N-terminal
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the N terminal region of Human Chordin, conjugated to KLH

  • Positive control
    • Human hepatocarcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab80146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
IHC-P 1/10 - 1/50.

Target

  • Function
    Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
  • Tissue specificity
    Expressed at the highest level in liver.
  • Sequence similarities
    Belongs to the chordin family.
    Contains 4 CHRD domains.
    Contains 4 VWFC domains.
  • Post-translational
    modifications
    Cleaved by tolloid proteases; cleavage participates to dorsoventral patterning during early development.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Chordin antibody
    • chrd antibody
    • CHRD_HUMAN antibody
    • MGC133038 antibody
    • Shortgastrulation protein antibody
    • SOG antibody
    see all

Images

  • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human hepatocarcinoma tissue using 1/10-1/50 ab80146, in conjunction with a peroxidase-conjugated secondary antibody, followed by DAB staining.

References

ab80146 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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