Anti-CHRDL1 antibody [3H1-F6-A10] (ab131189)

Overview

  • Product nameAnti-CHRDL1 antibody [3H1-F6-A10]See all CHRDL1 primary antibodies ...
  • Description
    Mouse monoclonal [3H1-F6-A10] to CHRDL1
  • Specificityab131189 detects endogenous levels of CHRDL1 and does not cross react with related proteins.
  • Tested applicationsICC/IF, WB, ELISAmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Purified recombinant Human CHRDL1 fragments expressed in E.coli.

  • Positive control
    • Rat kidney tissue lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.40
    Preservative: 0.2% Sodium azide
    Constituents: 49% Tris glycine, 50% Glycerol, 0.88% Sodium chloride
  • Concentration information loading...
  • PurityProtein G purified
  • Clonality Monoclonal
  • Clone number3H1-F6-A10
  • IsotypeIgG1
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab131189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
WB 1/1000. Predicted molecular weight: 51 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionAntagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
  • Tissue specificityExpressed in retinal pericytes.
  • Sequence similaritiesContains 3 VWFC domains.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • CHL antibody
    • chordin like 1 antibody
    • Chordin-like protein 1 antibody
    • CHRDL1 antibody
    • CRDL1_HUMAN antibody
    • dA141H5.1 antibody
    • neuralin 1 antibody
    • Neuralin-1 antibody
    • Neurogenesin-1 antibody
    • NRLN1 antibody
    • Ventroptin antibody
    • VOPT antibody
    see all

Anti-CHRDL1 antibody [3H1-F6-A10] images

  • Anti-CHRDL1 antibody [3H1-F6-A10] (ab131189) at 1/1000 dilution + Rat kidney tissue lysate

    Predicted band size : 51 kDa
  • Immunocytochemistry stain of Hela cells using ab131189(1:300).

References for Anti-CHRDL1 antibody [3H1-F6-A10] (ab131189)

ab131189 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"