Overview

  • Product nameAnti-CHRDL1 antibody
    See all CHRDL1 primary antibodies
  • Description
    Rabbit polyclonal to CHRDL1
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, between amino acids 5-35 from the N-terminal region of Human CHRDL1 (NP_660277).

  • Positive control
    • 293 cell line lysate, Human hepatocarcinoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab107008 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab107008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 51 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionAntagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
  • Tissue specificityExpressed in retinal pericytes.
  • Sequence similaritiesContains 3 VWFC domains.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • CHL antibody
    • chordin like 1 antibody
    • Chordin-like protein 1 antibody
    • CHRDL1 antibody
    • CRDL1_HUMAN antibody
    • dA141H5.1 antibody
    • neuralin 1 antibody
    • Neuralin-1 antibody
    • Neurogenesin-1 antibody
    • NRLN1 antibody
    • Ventroptin antibody
    • VOPT antibody
    see all

Anti-CHRDL1 antibody images

  • Anti-CHRDL1 antibody (ab107008) at 1/100 dilution + 293 cell line lysate at 35 µg

    Predicted band size : 51 kDa
  • Immunohistochemistry analysis in formalin fixed and paraffin embedded Human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. ab107008 at a dilution of 1/50.

References for Anti-CHRDL1 antibody (ab107008)

ab107008 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"