Overview

  • Product nameAnti-CHRDL1 antibodySee all CHRDL1 primary antibodies ...
  • Description
    Mouse monoclonal to CHRDL1
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 347-457 of Human CHRDL1

Properties

Applications

Our Abpromise guarantee covers the use of ab57933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAntagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
    • Tissue specificityExpressed in retinal pericytes.
    • Sequence similaritiesContains 3 VWFC domains.
    • Cellular localizationSecreted.
    • Target information above from: UniProt accession Q9BU40 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • Alternative names
      • CHL antibody
      • chordin like 1 antibody
      • Chordin-like protein 1 antibody
      • CHRDL1 antibody
      • CRDL1_HUMAN antibody
      • dA141H5.1 antibody
      • neuralin 1 antibody
      • Neuralin-1 antibody
      • Neurogenesin-1 antibody
      • NRLN1 antibody
      • Ventroptin antibody
      • VOPT antibody
      see all

    Anti-CHRDL1 antibody images



    • Predicted band size : 51 kDa
      CHRDL1 antibody (ab57933) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-CHRDL1 antibody (ab57933)

    ab57933 has not yet been referenced specifically in any publications.

    Product Wall

    Application Western blot
    Sample Mouse Tissue lysate - whole (white adipose tissue)
    Loading amount 8 µg
    Specification white adipose tissue
    Gel Running Conditions Reduced Denaturing (10%)
    Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 24°C
    Username

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    Verified customer

    Submitted May 21 2010

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"