FunctionTranscriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.
Tissue specificityExpressed in liver, heart, kidney, cerebellum and intestinal tissues.
Involvement in diseaseNote=WBSCR14 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR14 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
carbohydrate response element binding protein antibody
Carbohydrate responsive element binding protein antibody
Class D basic helix-loop-helix protein 14 antibody
MLX interacting protein like antibody
Mlx interactor antibody
MLX-interacting protein-like antibody
WBSCR 14 antibody
Williams Beuren syndrome chromosome region 14 antibody
Williams Beuren syndrome chromosome region 14 protein antibody
Williams-Beuren syndrome chromosomal region 14 protein antibody
WS basic helix loop helix leucine zipper protein antibody
WS basic-helix-loop-helix leucine zipper protein antibody
WS bHLH antibody
Anti-CHREBP antibody images
Western blot - CHREBP antibody (ab112944)
Anti-CHREBP antibody (ab112944) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg
Predicted band size : 93 kDa
References for Anti-CHREBP antibody (ab112944)
This product has been referenced in:
Airley RE et al. Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression. Br J Cancer110:715-23 (2014).
Read more (PubMed: 24366300) »