Overview

  • Product nameAnti-CHRFAM7A antibody
    See all CHRFAM7A primary antibodies
  • Description
    Rabbit polyclonal to CHRFAM7A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 180-229 (QRRCSLASVE MSAVAPPPAS NGNLLYIGFR GLDGVHCVPT PDSGVVCGRM) of Human CHRFAM7A (NP_683709).

  • Positive control
    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceThe nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. CHRFAM7A is encoded by a hybrid gene consisting of a duplication of exons 5 through 10 of the CHRNA7 gene fused 3-prime to a copy of the FAM7A gene (exons A through E). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel.
  • Cellular localizationMembrane; Multi-pass membrane protein.
  • Database links
  • Alternative names
    • Alpha 7 neuronal nicotinic acetylcholine receptor FAM7A hybrid antibody
    • CHRNA7 (cholinergic receptor nicotinic alpha 7 exons 5 10) and FAM7A (family with sequence similarity 7A exons A E) fusion antibody
    • CHRNA7 antibody
    • CHRNA7 DR1 antibody
    • CHRNA7 FAM7A fusion antibody
    • CHRNA7 FAM7A fusion protein antibody
    • D 10 antibody
    • D10 antibody
    • MGC120482 antibody
    • MGC120483 antibody
    see all

Anti-CHRFAM7A antibody images

  • Anti-CHRFAM7A antibody (ab85475) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
    Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.

References for Anti-CHRFAM7A antibody (ab85475)

ab85475 has not yet been referenced specifically in any publications.

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