Overview

  • Product nameAnti-CHRNA10 antibody
    See all CHRNA10 primary antibodies
  • Description
    Rabbit polyclonal to CHRNA10
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from Human CHRNA10.

  • Positive control
    • Extracts from A549 cells, COLO cells, HeLa cells and 293 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab110063 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 50 kDa.

Target

  • FunctionIonotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
  • Tissue specificityExpressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-10/CHRNA10 sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody
    • ACH10_HUMAN antibody
    • Alpha 10 nAChR antibody
    • Cholinergic receptor nicotinic alpha 10 antibody
    • Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody
    • Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody
    • CHRNA 10 antibody
    • CHRNA10 antibody
    • NACHR alpha 10 antibody
    • NACHR alpha-10 antibody
    • NACHRA10 antibody
    • Neuronal acetylcholine receptor protein subunit alpha 10 antibody
    • Neuronal acetylcholine receptor subunit alpha-10 antibody
    • Nicotinic acetylcholine receptor subunit alpha 10 antibody
    • Nicotinic acetylcholine receptor subunit alpha-10 antibody
    • OTTHUMP00000013620 antibody
    see all

Anti-CHRNA10 antibody images

  • All lanes : Anti-CHRNA10 antibody (ab110063) at 1/500 dilution

    Lane 1 : Extracts from A549 cells
    Lane 2 : Extracts from COLO cells
    Lane 3 : Extracts from 293 cells
    Lane 4 : Extracts from HeLa cells
    Lane 5 : Extracts from A549 cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 50 kDa

References for Anti-CHRNA10 antibody (ab110063)

ab110063 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"