Overview

  • Product nameAnti-Chromogranin A antibody
    See all Chromogranin A primary antibodies
  • Description
    Goat polyclonal to Chromogranin A
  • Tested applicationsWB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-QGAKERAHQQKKH

    , corresponding to internal sequence amino acids 85-97 of Human Chromogranin A (NP_001266.1).

  • Positive control
    • Human kidney lysate; Human small intestine and Human pancreas tissues

Properties

Applications

Our Abpromise guarantee covers the use of ab109993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 51 kDa).
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • FunctionPancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • Sequence similaritiesBelongs to the chromogranin/secretogranin protein family.
  • Post-translational
    modifications
    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • Cellular localizationSecreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt
  • Database links
  • FormAccording to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
  • Alternative names
    • beta Granin antibody
    • CgA antibody
    • CHG A antibody
    • Chga antibody
    • Chromogranin A parathyroid secretory protein 1 antibody
    • Chromogranin A precursor antibody
    • ChromograninA antibody
    • CMGA_HUMAN antibody
    • ER-37 antibody
    • Pancreastatin antibody
    • Parastatin antibody
    • Parathyroid secretory protein 1 antibody
    • Pituitary secretory protein I antibody
    • SP I antibody
    • SP-I antibody
    • SP1 antibody
    • SPI antibody
    • Vasostatin antibody
    • Vasostatin I antibody
    • Vasostatin II antibody
    see all

Anti-Chromogranin A antibody images

  • Anti-Chromogranin A antibody (ab109993) at 0.1 µg/ml + Human kidney lysate (in RIPA buffer) at 35 µg
    developed using the ECL technique

    Predicted band size : 51 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour
  • ab109993, at a concentration of 3.75 µg/ml, staining Chromogranin A in formalin fixed, paraffin embedded Human small intestine by Immunohistochemistry.
  • ab109993, at a concentration of 3.75 µg/ml, staining Chromogranin A in formalin fixed, paraffin embedded Human pancreas by Immunohistochemistry.

References for Anti-Chromogranin A antibody (ab109993)

ab109993 has not yet been referenced specifically in any publications.

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