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Overview

  • Product nameAnti-Chromogranin A antibodySee all Chromogranin A primary antibodies ...
  • Description
    Rabbit polyclonal to Chromogranin A
  • Tested applicationsSandwich ELISA, IHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    C-terminal half of Chromogranin A, purified from urine of patients with carcinoid syndrome.

  • Positive controlPancreas

Properties

Applications

Our Abpromise guarantee covers the use of ab17064 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Sandwich ELISA sELISA: Use a concentration of 0.5 µg/ml. Can be paired for Sandwich ELISA with Mouse monoclonal [23A1] to Chromogranin A (ab36997). For sandwich ELISA, use this antibody as Detection with ab36997 as Capture.
IHC-P IHC-P: 1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • FunctionPancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • Sequence similaritiesBelongs to the chromogranin/secretogranin protein family.
  • Post-translational
    modifications    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • Cellular localizationSecreted. Neuroendocrine and endocrine secretory granules.

    • Target information above from: UniProt accession P10645 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • FormAccording to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
    • Alternative names
        beta Granin antibodyCGA antibodyCHG A antibody
        CHGA antibodyChromogranin A parathyroid secretory protein 1 antibodyChromogranin A precursor antibodyChromograninA antibodyCMGA_HUMAN antibodyER-37 antibodyPancreastatin antibodyParastatin antibodyParathyroid secretory protein 1 antibodyPituitary secretory protein I antibodySP I antibodySP-I antibodySP1 antibodySPI antibodyVasostatin antibodyVasostatin I antibodyVasostatin II antibody
      see all

    Anti-Chromogranin A antibody images

    • Sandwich ELISA - Chromogranin A antibody (ab17064)
      Sandwich ELISA - Chromogranin A antibody (ab17064)
      Standard Curve for Chromogranin A (Analyte: ab85486) dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [23A1] to Chromogranin A (ab36997) at 1ug/ml and Detector Antibody Rabbit polyclonal to Chromogranin A (ab17064) at 0.5ug/ml. Concentration of ab17064 may vary from lot to lot; please use this curve as guideline.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chromogranin A antibody (ab17064)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chromogranin A antibody (ab17064)
      ab17064 staining Chromogranin A in formalin-fixed, paraffin-embedded Human pancreas tissue by Immunohistochemistry.

    Protocols

    References for Anti-Chromogranin A antibody (ab17064)

    This product has been referenced in:
    • Saqui-Salces M  et al. A high-fat diet regulates gastrin and acid secretion through primary cilia. FASEB J : (2012). IHC-P ; Mouse . Read more (PubMed: 22516298) »

    See 1 Publication for this product

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    What is the concentration?

    Thank you for your enquiry. The concentration of lot 151574 is 100 ug/ml. The amino acid sequence is considered commercially sensitive information. I hope this information helps, please do not hesitate to contact us if you need any more advice or i...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"