Anti-Chromogranin A antibody [LK2H10], prediluted (ab53464)

Overview

  • Product nameAnti-Chromogranin A antibody [LK2H10], prediluted
    See all Chromogranin A primary antibodies
  • Description
    Mouse monoclonal [LK2H10] to Chromogranin A, prediluted
  • Specificityab53464 recognises Chromogranin A and other Chromogranins.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human, Pig, Monkey
    Does not react with: Mouse, Rat, Sheep, Rabbit, Guinea pig
  • Immunogen

    Human Phaeochromocytoma (solid tissue)

  • Positive control
    • Adrenal medulla, anterior pituitary
  • General notes


    Stains hormone secreting cells (with the exception of Neurohypophysis) and all tumours derived from endocrine glands. Less intense staining usually is found in small cell lung carcinoma (SCLC), Merkel Cell Carcinoma and Neuroblastoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab53464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1.

Ready to use. No pre-treatment necessary.

Target

  • FunctionPancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • Sequence similaritiesBelongs to the chromogranin/secretogranin protein family.
  • Post-translational
    modifications
    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • Cellular localizationSecreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt
  • Database links
  • FormAccording to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
  • Alternative names
    • beta Granin antibody
    • betagranin (N-terminal fragment of chromogranin A) antibody
    • catestatin antibody
    • CgA antibody
    • CHG A antibody
    • Chga antibody
    • chromofungin antibody
    • Chromogranin A parathyroid secretory protein 1 antibody
    • Chromogranin A precursor antibody
    • ChromograninA antibody
    • CMGA_HUMAN antibody
    • ER-37 antibody
    • Pancreastatin antibody
    • Parastatin antibody
    • Parathyroid secretory protein 1 antibody
    • Pituitary secretory protein I antibody
    • Secretory protein I antibody
    • SP I antibody
    • SP-I antibody
    • SP1 antibody
    • SPI antibody
    • Vasostatin antibody
    • Vasostatin I antibody
    • Vasostatin II antibody
    see all

References for Anti-Chromogranin A antibody [LK2H10], prediluted (ab53464)

ab53464 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"