• Product nameAnti-CHST6 antibody
    See all CHST6 primary antibodies
  • Description
    Rabbit polyclonal to CHST6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 346-395 (QELCAGALQL LGYRPVYSED EQRNLALDLV LPRGLNGFTW ASSTASHPRN) of human CHST6 (NP_067628).

  • Positive control
    • 293T cell lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified by peptide affinity chromatography method.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab84555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionSulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.
  • Tissue specificityExpressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea.
  • Involvement in diseaseDefects in CHST6 are the cause of macular dystrophy, corneal, 1 (MCDC1) [MIM:217800]. An ocular disease characterized by bilateral, progressive corneal opacification, and reduced corneal sensitivity. Onset occurs in the first decade, usually between ages 5 and 9. Painful attacks with photophobia, foreign body sensations, and recurrent erosions occur in most patients. The disease is due to deposition of an unsulfated keratan sulfate both within the intracellular space (within the keratocytes and endothelial cells) and in the extracellular corneal stroma. Macular corneal dystrophy is divided into the clinically indistinguishable types I, IA, and II based on analysis of the normally sulfated, or antigenic, keratan sulfate levels in serum and immunohistochemical evaluation of the cornea. Patients with types I and IA macular corneal dystrophy have undetectable serum levels of antigenic keratan sulfate, whereas those with type II macular corneal dystrophy have normal or low levels, depending on the population examined. Note=CHST6 homozygous missense mutations have been observed in patients with macular corneal dystrophy type I, while type II patients show a large deletion and replacement in the upstream region of CHST6. The only missense mutation for type II is Cys-50, which is heterozygous with a replacement in the upstream region on the other allele of CHST6.
  • Sequence similaritiesBelongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
  • Cellular localizationGolgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C GlcNAc6ST antibody
    • C-GlcNAc6ST antibody
    • Carbohydate sulfotransferase 6 antibody
    • Carbohydrate (N acetylglucosamine 6 O) sulfotransferase 6 antibody
    • Carbohydrate sulfotransferase 6 antibody
    • CHST6 antibody
    • CHST6_HUMAN antibody
    • Corneal GlcNAc6-sulfotransferase antibody
    • Corneal N acetylglucosamine 6 sulfotransferase antibody
    • Corneal N-acetylglucosamine-6-O-sulfotransferase antibody
    • Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 4 beta antibody
    • Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta antibody
    • GlcNAc6ST 5 antibody
    • GlcNAc6ST-5 antibody
    • Gn6st-5 antibody
    • GST4 beta antibody
    • GST4-beta antibody
    • hCGn6ST antibody
    • N-acetylglucosamine 6-O-sulfotransferase 5 antibody
    see all

Anti-CHST6 antibody images

  • Anti-CHST6 antibody (ab84555) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 44 kDa
    Observed band size : 44 kDa

References for Anti-CHST6 antibody (ab84555)

ab84555 has not yet been referenced specifically in any publications.

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