Overview

  • Product nameAnti-Chymotrypsin antibody [4E1]
    See all Chymotrypsin primary antibodies
  • Description
    Mouse monoclonal [4E1] to Chymotrypsin
  • Tested applicationsSuitable for: IHC-P, ICC/IF, IHC-Fr, ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Full length native pancreatic protein (purified) (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab35694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IHC-Fr 1/100 - 1/800.
ELISA 1/20000.
WB 1/400 - 1/4000. Predicted molecular weight: 29 kDa.

Target

  • FunctionHas chymotrypsin-type protease activity and hypocalcemic activity.
  • Tissue specificityPancreas.
  • Involvement in diseaseVariations in CTRC influence susceptibility to chronic pancreatitis [MIM:167800]. Chronic pancreatitis is a persistent inflammatory disorder characterized by permanent destruction of the pancreatic parenchyma.
  • Sequence similaritiesBelongs to the peptidase S1 family. Elastase subfamily.
    Contains 1 peptidase S1 domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • Caldecrin antibody
    • Chymotrypsin C antibody
    • Chymotrypsin-C antibody
    • ChymotrypsinC antibody
    • CLCR antibody
    • Ctrc antibody
    • CTRC_HUMAN antibody
    • ELA 4 antibody
    • ELA4 antibody
    • Elastase 4 antibody
    • Elastase IV antibody
    • Elastase4 antibody
    • ElastaseIV antibody
    • OTTHUMP00000044526 antibody
    • Serum calcium decreasing factor antibody
    see all

References for Anti-Chymotrypsin antibody [4E1] (ab35694)

This product has been referenced in:
  • Lacruz RS  et al. New paradigms on the transport functions of maturation-stage ameloblasts. J Dent Res 92:122-9 (2013). IHC-P ; Mouse . Read more (PubMed: 23242231) »
  • Altshuler AE  et al. Removal of luminal content protects the small intestine during hemorrhagic shock but is not sufficient to prevent lung injury. Physiol Rep 1:e00109 (2013). WB ; Rat . Read more (PubMed: 24303180) »

See all 3 Publications for this product

Product Wall

Thank you for contacting Abcam regarding our anti-chymotrypsin antibodies. I have compared the human and porcine chemotrypsin sequences and overall, they share 84% identity.  Unfortunately, we have not mapped the epitopes recognized by these antibo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"