• Product nameAnti-Cip4 antibody
    See all Cip4 primary antibodies
  • Description
    Rabbit polyclonal to Cip4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids 114-145 of Human Cip4 (NP_004231.1, Q15642).

  • Positive control
    • K562 cell line lysates


Associated products


Our Abpromise guarantee covers the use of ab123392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 68 kDa.


  • FunctionRequired for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
  • Tissue specificityExpressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea.
  • Sequence similaritiesBelongs to the FNBP1 family.
    Contains 1 FCH domain.
    Contains 1 REM (Hr1) repeat.
    Contains 1 SH3 domain.
  • Post-translational
    Tyrosine phosphorylated. Also phosphorylated by PKA.
  • Cellular localizationCytoplasm > perinuclear region and Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection > phagocytic cup. Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity). Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cdc42 interacting protein 4 antibody
    • Cdc42 interaction protein 4 long isoform antibody
    • Cdc42-interacting protein 4 antibody
    • CG11341 antibody
    • CG15015 PA antibody
    • Cip 4 antibody
    • CIP4 antibody
    • CIP4_HUMAN antibody
    • DCIP4 antibody
    • hSTP antibody
    • Protein Felic antibody
    • Salt tolerant protein antibody
    • Salt tolerator antibody
    • STOT antibody
    • STP antibody
    • Thyroid hormone receptor interactor 10 antibody
    • Thyroid receptor interacting protein 10 antibody
    • Thyroid receptor-interacting protein 10 antibody
    • TR-interacting protein 10 antibody
    • TRIP 10 antibody
    • TRIP-10 antibody
    • trip10 antibody
    • Truncated Cdc42 interaction protein 4 antibody
    see all

Anti-Cip4 antibody images

  • Anti-Cip4 antibody (ab123392) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 68 kDa

References for Anti-Cip4 antibody (ab123392)

ab123392 has not yet been referenced specifically in any publications.

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