• Product nameAnti-Cip4 antibody [EPR1966(2)]
    See all Cip4 primary antibodies
  • Description
    Rabbit monoclonal [EPR1966(2)] to Cip4
  • SpecificityThe antibody has been tested in our lab in mouse and rat species without satisfactory results. Therefore, we do not recommend this antibody in these species.
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human Cip4

  • Positive control
    • WB: JAR, HepG2, TF1 and HeLa cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.


Associated products


Our Abpromise guarantee covers the use of ab108277 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 80 kDa (predicted molecular weight: 68 kDa).
  • Application notesIs unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • FunctionRequired for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
    • Tissue specificityExpressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea.
    • Sequence similaritiesBelongs to the FNBP1 family.
      Contains 1 FCH domain.
      Contains 1 REM (Hr1) repeat.
      Contains 1 SH3 domain.
    • Post-translational
      Tyrosine phosphorylated. Also phosphorylated by PKA.
    • Cellular localizationCytoplasm > perinuclear region and Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection > phagocytic cup. Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity). Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cdc42 interacting protein 4 antibody
      • Cdc42 interaction protein 4 long isoform antibody
      • Cdc42-interacting protein 4 antibody
      • CG11341 antibody
      • CG15015 PA antibody
      • Cip 4 antibody
      • CIP4 antibody
      • CIP4_HUMAN antibody
      • DCIP4 antibody
      • hSTP antibody
      • Protein Felic antibody
      • Salt tolerant protein antibody
      • Salt tolerator antibody
      • STOT antibody
      • STP antibody
      • Thyroid hormone receptor interactor 10 antibody
      • Thyroid receptor interacting protein 10 antibody
      • Thyroid receptor-interacting protein 10 antibody
      • TR-interacting protein 10 antibody
      • TRIP 10 antibody
      • TRIP-10 antibody
      • trip10 antibody
      • Truncated Cdc42 interaction protein 4 antibody
      see all

    Anti-Cip4 antibody [EPR1966(2)] images

    • All lanes : Anti-Cip4 antibody [EPR1966(2)] (ab108277) at 1/1000 dilution

      Lane 1 : JAR lysate
      Lane 2 : HepG2 lysate
      Lane 3 : TF1 lysate
      Lane 4 : HeLa lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 68 kDa

    References for Anti-Cip4 antibody [EPR1966(2)] (ab108277)

    ab108277 has not yet been referenced specifically in any publications.

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