Overview

  • Product nameAnti-CKAP1 antibody
    See all CKAP1 primary antibodies
  • Description
    Rabbit polyclonal to CKAP1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cat, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 37 - 86 (FKCKLELVVG SPASCMELEL GADDKFYSKL QEDALLGSYP DDGCRIH) of Mouse CKAP1 (NP_079824).

  • Positive control
    • Mouse thymus lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab113962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionBinds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
  • Tissue specificityFound in most tissues.
  • Sequence similaritiesBelongs to the TBCB family.
    Contains 1 CAP-Gly domain.
  • Post-translational
    modifications
    Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.
    Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.
  • Information by UniProt
  • Database links
  • Alternative names
    • CG22 antibody
    • CKAPI antibody
    • Cytoskeleton associated protein 1 antibody
    • Cytoskeleton associated protein CKAPI antibody
    • Cytoskeleton-associated protein 1 antibody
    • Cytoskeleton-associated protein CKAPI antibody
    • Tbcb antibody
    • TBCB_HUMAN antibody
    • Tubulin folding cofactor B antibody
    • Tubulin specific chaperone B antibody
    • Tubulin-folding cofactor B antibody
    • Tubulin-specific chaperone B antibody
    see all

Anti-CKAP1 antibody images

  • Anti-CKAP1 antibody (ab113962) at 1 µg/ml + Mouse thymus lysate at 10 µg

    Predicted band size : 27 kDa

References for Anti-CKAP1 antibody (ab113962)

ab113962 has not yet been referenced specifically in any publications.

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