Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Sequence
      C-SATHSGYRLNDYV

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45474 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Claudin 14 antibody (ab19035)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • AI851731
    • Claudin 14
    • Claudin-14
    • CLD14_HUMAN
    • CLDN 14
    • CLDN14
    • DFNB 29
    • DFNB29
    • Human CLDN14 gene
    • MGC109472
    • OTTHUMP00000109046
    • OTTHUMP00000109049
    • OTTMUSP00000021531
    • UNQ777/PRO1571
    see all
  • Function
    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
  • Tissue specificity
    Liver, kidney. Also found in ear.
  • Involvement in disease
    Defects in CLDN14 are the cause of deafness autosomal recessive type 29 (DFNB29) [MIM:605608]. DFNB29 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • Sequence similarities
    Belongs to the claudin family.
  • Cellular localization
    Cell junction > tight junction. Cell membrane.
  • Information by UniProt

References for Claudin 14 peptide (ab45474)

ab45474 has not yet been referenced specifically in any publications.

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