Recombinant
RabMAb

Anti-Claudin 17 antibody [EPR15483] (ab186744)

Overview

  • Product name
    Anti-Claudin 17 antibody [EPR15483]
    See all Claudin 17 primary antibodies
  • Description
    Rabbit monoclonal [EPR15483] to Claudin 17
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Claudin 17 aa 150 to the C-terminus. The exact sequence is proprietary.
    Database link: P56750

  • Positive control
    • Human muscle and fetal kidney lysates; Rat kidney, spleen and Raw 264.7 cell lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    EPR15483
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab186744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).

Target

  • Relevance
    Claudin proteins are a family of transmembrane proteins associated with tight junctions, and different tissues exhibit different Claudin composition. There are 18 homolgs present in humans, and mutations in any of these proteins cause a variety of human disease, this indicates their physiological importance. CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.
  • Cellular localization
    Integral membrane protein. Tight junctions.
  • Database links
  • Alternative names
    • CLDN17 antibody
    • Human CLDN17 gene for claudin 17 antibody

Images

  • Anti-Claudin 17 antibody [EPR15483] (ab186744) at 1/10000 dilution + Human muscle lysate at 20 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 25 kDa
    Observed band size: 25 kDa

  • Anti-Claudin 17 antibody [EPR15483] (ab186744) at 1/1000 dilution + Human fetal kidney lysate at 10 µg

    Secondary
    Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size: 25 kDa
    Observed band size: 25 kDa

  • All lanes : Anti-Claudin 17 antibody [EPR15483] (ab186744) at 1/1000 dilution

    Lane 1 : Rat kidney lysate
    Lane 2 : Rat spleen lysate
    Lane 3 : Raw 264.7 cell lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 25 kDa
    Observed band size: 25 kDa

References

ab186744 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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