Anti-Claudin 5 (phospho Y217) antibody (ab111336)

Overview

  • Product nameAnti-Claudin 5 (phospho Y217) antibody
    See all Claudin 5 primary antibodies
  • Description
    Rabbit polyclonal to Claudin 5 (phospho Y217)
  • Specificityab111336 detects endogenous levels of Claudin 5 only when phosphorylated at tyrosine 217.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from C-terminal region of Human Claudin 5 around the phosphorylation site of Tyr217 (K-N-YP-V).

  • Positive control
    • Human brain tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab111336 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111336 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionPlays a major role in tight junction-specific obliteration of the intercellular space.
  • Sequence similaritiesBelongs to the claudin family.
  • Cellular localizationCell junction > tight junction. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Androgen withdrawal and apoptosis induced protein RVP1 like antibody
    • AWAL antibody
    • BEC 1 antibody
    • BEC1 antibody
    • Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody
    • Claudin-5 antibody
    • Claudin5 antibody
    • CLD5_HUMAN antibody
    • CLDN 5 antibody
    • Cldn5 antibody
    • CPETR L1 antibody
    • CPETRL 1 antibody
    • CPETRL1 antibody
    • TMDVCF antibody
    • TMVCF antibody
    • Transmembrane protein deleted in VCFS antibody
    • Transmembrane protein deleted in velocardiofacial syndrome antibody
    see all

Anti-Claudin 5 (phospho Y217) antibody images

  • Immunohistochemistry analysis of paraffin-embedded Human brain tissue using ab111336 at a dilution of 1/50. Left panel shows staining without immunizing peptide right panel shows staining with immunizing peptide.

References for Anti-Claudin 5 (phospho Y217) antibody (ab111336)

ab111336 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111336.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"