• Product nameAnti-Claudin 6 antibody
    See all Claudin 6 primary antibodies
  • Description
    Rabbit polyclonal to Claudin 6
  • Tested applicationsSuitable for: WB, ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal sequence of human Claudin 6.

  • Positive control
    • human ovarian tissue, HUVEC cells, extracts from Jurkat cells.



Our Abpromise guarantee covers the use of ab75055 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 23 kDa).
ELISA 1/40000.
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.


  • FunctionPlays a major role in tight junction-specific obliteration of the intercellular space.
  • Sequence similaritiesBelongs to the claudin family.
  • Cellular localizationCell junction > tight junction. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Claudin-6 antibody
    • Claudin6 antibody
    • CLD6_HUMAN antibody
    • CLDN 6 antibody
    • CLDN6 antibody
    • OTTHUMP00000159248 antibody
    • Skullin 2 antibody
    • Skullin antibody
    • UNQ757/PRO1488 antibody
    see all

Anti-Claudin 6 antibody images

  • Human ovarian tissue with ab75055 at 1/50 dilution, in the absence and presence of the immunising peptide.
  • Huvec cells with ab75055 at 1/500 dilution, in the absence and presence of the immunising peptide.
  • All lanes : Anti-Claudin 6 antibody (ab75055) at 1/500 dilution

    Lane 1 : extracts from Jurkat cells
    Lane 2 : extracts from Jurkat cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 23 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)
    Additional bands at : <19 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Claudin 6 antibody (ab75055)

This product has been referenced in:
  • Florimond A  et al. Human hepatic stellate cells are not permissive for hepatitis C virus entry and replication. Gut N/A:N/A (2014). Human . Read more (PubMed: 25063678) »
  • Sarhan MA  et al. Differential expression of candidate virus receptors in human T lymphocytes prone or resistant to infection with patient-derived hepatitis C virus. PLoS One 8:e62159 (2013). WB ; Human . Read more (PubMed: 23626783) »

See all 2 Publications for this product

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate pH6 25C 100C 20 min
Sample Human Tissue sections (small intestine)
Specification small intestine
Blocking step H2O2 as blocking agent for 10 minute(s) · Concentration: 3% · Temperature: 25°C
Fixative Formaldehyde

Abcam user community

Verified customer

Submitted Aug 07 2014

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (Pancreas)
Specification Pancreas
Fixative Paraformaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Citrate pH 6.0
Permeabilization No
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 20% · Temperature: 22°C

Abcam user community

Verified customer

Submitted Mar 24 2010