FunctionPlays a major role in tight junction-specific obliteration of the intercellular space.
Tissue specificityExpressed in the epididymis, mainly in the caput segment.
Sequence similaritiesBelongs to the claudin family.
Cellular localizationCell junction > tight junction. Cell membrane. Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells.