Overview

  • Product name
    Anti-Clavesin 1 + 2 antibody
    See all Clavesin 1 + 2 primary antibodies
  • Description
    Rabbit polyclonal to Clavesin 1 + 2
  • Specificity
    Specific for Clavesin 1/2 protein doublet in Western blots of Rat brain lysate. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are Clavesin 1 and 2, respectively.
  • Tested applications
    Suitable for: WB, ICCmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide from the C terminus of Rat Clavesin 1.

  • Positive control
    • Rat hippocampal homogenate; Rat brain lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 41 kDa.
ICC 1/50.

Target

  • Relevance
    Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009). Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008).
  • Cellular localization
    Golgi Apparatus, Cytoplasmic vesicle, Endosome, Membrane.
  • Database links
  • Alternative names
    • bA160A10.4 antibody
    • C6orf212 antibody
    • C6orf213 antibody
    • Clavesin 1 antibody
    • Clavesin 2 antibody
    • CRALBPL antibody
    • FLJ37248 antibody
    • MGC120572 antibody
    • MGC34646 antibody
    • OTTHUMP00000017122 antibody
    • Retinaldehyde binding protein 1 like 1 antibody
    • Retinaldehyde binding protein 1 like 2 antibody
    • RLBP1L1 antibody
    • RLBP1L2 antibody
    see all

Images

  • Anti-Clavesin 1 + 2 antibody (ab106557) at 1/1000 dilution + Rat hippocampal homogenate

    Predicted band size : 41 kDa

References

ab106557 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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