Overview

  • Product nameAnti-CLCA4 antibody
    See all CLCA4 primary antibodies
  • Description
    Rabbit polyclonal to CLCA4
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: WVGMVHFDST ATIVNKLIQI KSSDERNTLM AGLPTYPLGG TSICSGIKYA FQVIGELHSQ LDGSEVLLLT DGEDNTASSC IDEV, corresponding to amino acids 56-139 of Human CLCA4.

  • Positive control
    • Human duodenum.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferPreservative: 0.02% Sodium azide
    Constituents: 60% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMay be involved in mediating calcium-activated chloride conductance.
  • Tissue specificityPrimarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp.
  • Sequence similaritiesBelongs to the CLCR family.
    Contains 1 VWFA domain.
  • Post-translational
    modifications
    Processed at a monobasic residue to yield a larger N-terminal and a smaller C-terminal cleavage products of 90 to 110 and 30 to 35 kDa, respectively.
  • Cellular localizationCell membrane. Apical cell membrane. Secreted. The C-terminus 30 kDa form is anchored to the membrane (By similarity). The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 30 kDa form antibody
    • CaCC-2 antibody
    • Calcium-activated chloride channel family member 4 antibody
    • Calcium-activated chloride channel protein 2 antibody
    • Calcium-activated chloride channel regulator 4 antibody
    • Clca4 antibody
    • CLCA4_HUMAN antibody
    • hCaCC-2 antibody
    • hCLCA4 antibody
    see all

Anti-CLCA4 antibody images

  • ab121524, at 1/10 dilution, staining human duodenum by immunohistochemistry on paraffin embebbed tissues (IHC-P).

References for Anti-CLCA4 antibody (ab121524)

ab121524 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"