Overview

  • Product nameAnti-CLCN6 antibody
    See all CLCN6 primary antibodies
  • Description
    Rabbit polyclonal to CLCN6
  • Specificityab75048 detects endogenous levels of total CLCN6 protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthesized peptide derived from an internal region of human CLCN6.

  • Positive control
    • Extracts from COS-7 and HT-29 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab75048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 97 kDa.
ELISA 1/40000.

Target

  • FunctionChloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter.
  • Tissue specificityTestis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.
  • Sequence similaritiesBelongs to the chloride channel (TC 2.A.49) family. ClC-6/CLCN6 subfamily.
    Contains 2 CBS domains.
  • Post-translational
    modifications
    N-glycosylated on several asparagine residues.
  • Cellular localizationEndosome membrane. Detected in detergent-resistant lipid rafts.
  • Information by UniProt
  • Database links
  • Alternative names
    • Chloride channel 6 antibody
    • Chloride channel protein 6 antibody
    • Chloride channel voltage sensitive 6 antibody
    • Chloride transport protein 6 antibody
    • ClC 6 antibody
    • ClC-6 antibody
    • ClC6 antibody
    • CLCN6 antibody
    • CLCN6_HUMAN antibody
    • KIAA0046 antibody
    see all

Anti-CLCN6 antibody images

  • All lanes : Anti-CLCN6 antibody (ab75048) at 1/500 dilution

    Lane 1 : extracts from COS-7 cells
    Lane 2 : extracts from HT-29 cells
    Lane 3 : extracts from COS-7 cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 97 kDa
    Observed band size : 97 kDa

References for Anti-CLCN6 antibody (ab75048)

ab75048 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"