Anti-Cleavage stimulation factor 2 antibody (ab74406)

Overview

  • Product nameAnti-Cleavage stimulation factor 2 antibody
    See all Cleavage stimulation factor 2 primary antibodies
  • Description
    Rabbit polyclonal to Cleavage stimulation factor 2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis , Platypus (Ornithorhynchus anatinus)
  • Immunogen

    Synthetic peptide corresponding to a region between residue 527 and 577 of human Cleavage stimulation factor 2 (NP_001316.1)

  • Positive control
    • Human colon adenocarcinoma and mouse teratoma tissue. Other human tissues which may be suitable are: Breast Carcinoma, Colon Carcinoma, Ewing Sarcoma, Linitis Plastica Stomach Cancer, Non-Small Cell Lung Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma, Skin Basal Cell Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma and Testicular Seminoma.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab74406 was affinity purified using an epitope specific to Cleavage stimulation factor 2 immobilized on solid support.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab74406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.
    ab74406 is likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionOne of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs.
    • Sequence similaritiesContains 1 RRM (RNA recognition motif) domain.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus. Localized with DDX1 in cleavage bodies.
    • Information by UniProt
    • Database links
    • Alternative names
      • betaCstF 64 variant 2 antibody
      • CF-1 64 kDa subunit antibody
      • CF1 64 kDa subunit antibody
      • Cleavage stimulation factor 64 kDa subunit antibody
      • Cleavage stimulation factor subunit 2 antibody
      • Cleavage stimulation factor, 3' pre RNA, subunit 2, 64kDa antibody
      • CSTF 2 antibody
      • CstF 64 antibody
      • CSTF 64 kDa subunit antibody
      • CstF-64 antibody
      • CSTF2 antibody
      • CSTF2_HUMAN antibody
      • MGC188397 antibody
      see all

    Anti-Cleavage stimulation factor 2 antibody images

    • ab74406, at 1/250 dilution, staining Cleavage stimulation factor 2 in formalin fixed, paraffin embedded human colon adenocarcinoma tissue by Immunohistochemistry. Detection: DAB staining.
    • ab74406, at 1/250 dilution, staining Cleavage stimulation factor 2 in formalin fixed, paraffin embedded mouse teratoma tissue by Immunohistochemistry. Detection: DAB staining.

    References for Anti-Cleavage stimulation factor 2 antibody (ab74406)

    ab74406 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"