The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500.
FunctionOne of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA.
Sequence similaritiesContains 6 WD repeats.
DomainThe WD6 domain is required for interaction with BARD1. WD domains are responsible for interaction with CSTF3. N-terminus mediates homodimerization.
Post-translational modificationsThe N-terminus is blocked.