Overview

  • Product name
  • Description
    Rabbit polyclonal to CLEC12B
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 245-276 of Human CLEC12B (NP_001123470.1, NP_995324.2)

  • Positive control
    • K562 cell lysate and mouse testis tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab110694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 32 kDa.

Target

  • Function
    Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
  • Tissue specificity
    Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis.
  • Sequence similarities
    Contains 1 C-type lectin domain.
  • Domain
    Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-type lectin domain family 12 member B antibody
    • CL12B_HUMAN antibody
    • CLEC12B antibody
    • Macrophage antigen H antibody
    • UNQ5782 antibody
    see all

Images

  • Anti-CLEC12B antibody (ab110694) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 32 kDa
  • Anti-CLEC12B antibody (ab110694) at 1/100 dilution + Mouse testis tissue lysate at 35 µg

    Predicted band size : 32 kDa

References

ab110694 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab110694.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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