Overview

  • Product nameAnti-CLEC12B antibody
    See all CLEC12B primary antibodies
  • Description
    Rabbit polyclonal to CLEC12B
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 245-276 of Human CLEC12B (NP_001123470.1, NP_995324.2)

  • Positive control
    • K562 cell lysate and mouse testis tissue lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab110694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 32 kDa.

Target

  • FunctionCell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
  • Tissue specificityDetected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • DomainContains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-type lectin domain family 12 member B antibody
    • CL12B_HUMAN antibody
    • CLEC12B antibody
    • Macrophage antigen H antibody
    • UNQ5782 antibody
    see all

Anti-CLEC12B antibody images

  • Anti-CLEC12B antibody (ab110694) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 32 kDa
  • Anti-CLEC12B antibody (ab110694) at 1/100 dilution + Mouse testis tissue lysate at 35 µg

    Predicted band size : 32 kDa

References for Anti-CLEC12B antibody (ab110694)

ab110694 has not yet been referenced specifically in any publications.

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