Overview

  • Product nameAnti-CLEC2D antibody
    See all CLEC2D primary antibodies
  • Description
    Goat polyclonal to CLEC2D
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Synthetic peptide, conjugated to KLH corresponding to internal sequence amino acids of Human CLEC2D.

  • Positive control
    • Human placenta and tonsil tissues.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab111105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/16000.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionReceptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
  • Tissue specificityDetected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T and B lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Cellular localizationEndoplasmic reticulum and Cell membrane. Cell surface.
  • Information by UniProt
  • Database links
  • Alternative names
    • C type lectin related f antibody
    • C type lectin superfamily 2, member D antibody
    • C-type lectin domain family 2 member D antibody
    • CLAX antibody
    • CLC2D_HUMAN antibody
    • CLEC2D antibody
    • CLEC2D protein antibody
    • Clec2d5 antibody
    • L LT1 antibody
    • Lectin like NK cell receptor antibody
    • Lectin like transcript 1 antibody
    • Lectin-like NK cell receptor antibody
    • Lectin-like transcript 1 antibody
    • LLT-1 antibody
    • LLT1 antibody
    • OCIL antibody
    • Osteoclast inhibitory lectin antibody
    see all

Anti-CLEC2D antibody images

  • ab111105, at 3.75µg/ml, staining CLED2D in formalin-fixed, paraffin-embedded Human Placenta tissue by Immunohistochemistry.
  • ab111105, at 3.75µg/ml, staining CLED2D in formalin-fixed, paraffin-embedded Human Tonnsil tissue by Immunohistochemistry.

References for Anti-CLEC2D antibody (ab111105)

ab111105 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111105.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"