Overview

  • Product name
  • Description
    Goat polyclonal to CLEC2D
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Synthetic peptide, conjugated to KLH corresponding to internal sequence amino acids of Human CLEC2D.

  • Positive control
    • Human placenta and tonsil tissues.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/16000.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
  • Tissue specificity
    Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T and B lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
  • Sequence similarities
    Contains 1 C-type lectin domain.
  • Cellular localization
    Endoplasmic reticulum and Cell membrane. Cell surface.
  • Information by UniProt
  • Database links
  • Alternative names
    • C type lectin related f antibody
    • C type lectin superfamily 2, member D antibody
    • C-type lectin domain family 2 member D antibody
    • CLAX antibody
    • CLC2D_HUMAN antibody
    • CLEC2D antibody
    • CLEC2D protein antibody
    • Clec2d5 antibody
    • L LT1 antibody
    • Lectin like NK cell receptor antibody
    • Lectin like transcript 1 antibody
    • Lectin-like NK cell receptor antibody
    • Lectin-like transcript 1 antibody
    • LLT-1 antibody
    • LLT1 antibody
    • OCIL antibody
    • Osteoclast inhibitory lectin antibody
    see all

Images

  • ab111105, at 3.75µg/ml, staining CLED2D in formalin-fixed, paraffin-embedded Human Placenta tissue by Immunohistochemistry.
  • ab111105, at 3.75µg/ml, staining CLED2D in formalin-fixed, paraffin-embedded Human Tonnsil tissue by Immunohistochemistry.

References

ab111105 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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