Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab76529 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
    • Tissue specificity
      Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T and B lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
    • Sequence similarities
      Contains 1 C-type lectin domain.
    • Cellular localization
      Endoplasmic reticulum and Cell membrane. Cell surface.
    • Information by UniProt
    • Database links
    • Alternative names
      • C type lectin related f antibody
      • C type lectin superfamily 2, member D antibody
      • C-type lectin domain family 2 member D antibody
      • CLAX antibody
      • CLC2D_HUMAN antibody
      • CLEC2D antibody
      • CLEC2D protein antibody
      • Clec2d5 antibody
      • L LT1 antibody
      • Lectin like NK cell receptor antibody
      • Lectin like transcript 1 antibody
      • Lectin-like NK cell receptor antibody
      • Lectin-like transcript 1 antibody
      • LLT-1 antibody
      • LLT1 antibody
      • OCIL antibody
      • Osteoclast inhibitory lectin antibody
      see all

    Images

    • Anti-CLEC2D antibody (ab76529) at 1 µg/ml + Human spleen tissue lysate - total protein (ab29699) at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 21 kDa
      Observed band size : 21 kDa
      Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 20 minutes

    References

    ab76529 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab76529.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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