Recombinant
RabMAb

Anti-CLEC2D antibody [EPR6584(2)] (ab151738)

Overview

  • Product name
    Anti-CLEC2D antibody [EPR6584(2)]
    See all CLEC2D primary antibodies
  • Description
    Rabbit monoclonal [EPR6584(2)] to CLEC2D
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human CLEC2D (UniProt: Q9UHP7).

  • Positive control
    • Human lymph node, Saos2, and U-87 MG lysates; Saos2 cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20ºC.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR6584(2)
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab151738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
    • Tissue specificity
      Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T and B lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
    • Sequence similarities
      Contains 1 C-type lectin domain.
    • Cellular localization
      Endoplasmic reticulum and Cell membrane. Cell surface.
    • Information by UniProt
    • Database links
    • Alternative names
      • C type lectin related f antibody
      • C type lectin superfamily 2, member D antibody
      • C-type lectin domain family 2 member D antibody
      • CLAX antibody
      • CLC2D_HUMAN antibody
      • CLEC2D antibody
      • CLEC2D protein antibody
      • Clec2d5 antibody
      • L LT1 antibody
      • Lectin like NK cell receptor antibody
      • Lectin like transcript 1 antibody
      • Lectin-like NK cell receptor antibody
      • Lectin-like transcript 1 antibody
      • LLT-1 antibody
      • LLT1 antibody
      • OCIL antibody
      • Osteoclast inhibitory lectin antibody
      see all

    Images

    • All lanes : Anti-CLEC2D antibody [EPR6584(2)] (ab151738) at 1/1000 dilution

      Lane 1 : Human lymph node lysate
      Lane 2 : Saos2 cell lysate
      Lane 3 : U-87 MG cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 22 kDa

    • Flow cytometric analysis of permeabilized Saos2 cells labeling CLEC2D with ab151738 at 1/10 dilution (red), compared to a nonspecific control antibody (green).

    References

    ab151738 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab151738.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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