Overview

  • Product nameAnti-CLEC4E antibody
    See all CLEC4E primary antibodies
  • Description
    Mouse polyclonal to CLEC4E
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human) with tag

  • Positive control
    • Recombinant tagged CLEC4E.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 50% Glycerol, Whole serum
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab66128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: Use at an assay dependent dilution.
    WB: 1/1000 - 1/2500. Predicted molecular weight: 25 kDa.

    This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionC-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
    • Sequence similaritiesContains 1 C-type lectin domain.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • C type lectin domain family 4 member E antibody
      • C type lectin superfamily member 9 antibody
      • C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody
      • C-type lectin domain family 4 member E antibody
      • C-type lectin superfamily member 9 antibody
      • CLC4E_HUMAN antibody
      • CLEC 4E antibody
      • Clec4e antibody
      • CLECSF9 antibody
      • Macrophage inducible C type lectin antibody
      • Macrophage-inducible C-type lectin antibody
      • MINCLE antibody
      see all

    Anti-CLEC4E antibody images



    • Predicted band size : 25 kDa

    References for Anti-CLEC4E antibody (ab66128)

    ab66128 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"