• Product nameAnti-CLEC5A antibody
    See all CLEC5A primary antibodies
  • Description
    Mouse polyclonal to CLEC5A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human CLEC5A protein (NP_037384.1).

  • Positive control
    • Human liver tissue lysate and CLEC5A transfected 293T cell line lysate.



Our Abpromise guarantee covers the use of ab89060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa.


  • FunctionFunctions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
  • Tissue specificityExpressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U-937 and Mono-Mac-6, but not in cell lines of other origins. Expression is down-regulated when monocytes differentiate into dendritic cells.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Post-translational
    N-glycosylated. Contains sialic acid residues.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C type lectin domain family 5 member A antibody
    • C-type lectin domain family 5 member A antibody
    • C-type lectin superfamily member 5 antibody
    • CLC5A_HUMAN antibody
    • CLEC5 A antibody
    • CLEC5A antibody
    • CLECSF 5 antibody
    • CLECSF5 antibody
    • MDL 1 antibody
    • MDL-1 antibody
    • MDL1 antibody
    • Myeloid DAP12 associating lectin antibody
    • Myeloid DAP12-associating lectin 1 antibody
    see all

Anti-CLEC5A antibody images

  • Anti-CLEC5A antibody (ab89060) at 1 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 22 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-CLEC5A antibody (ab89060) at 1 µg/ml

    Lane 1 : CLEC5A transfected 293T cell line lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 22 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 36 kDa. We are unsure as to the identity of these extra bands.

References for Anti-CLEC5A antibody (ab89060)

ab89060 has not yet been referenced specifically in any publications.

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To our knowledge, ab89060 has not been tested in Flow Cytometry. However by participating in our AbTrial program you can now use our products in an untested application or species with...

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