Overview

  • Product name
    Anti-CLEC9A antibody [7H11]
    See all CLEC9A primary antibodies
  • Description
    Rat monoclonal [7H11] to CLEC9A
  • Tested applications
    Suitable for: ELISA, Flow Cyt, IP, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    RBL-2H3 cells expressing Mouse CLEC9A fused to an HA epitope.

  • General notes
    Growth Conditions: RPMI + 10% FCS + Pen + Strep + Glutamine + 2-ME.

Properties

Applications

Our Abpromise guarantee covers the use of ab104909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab18407-Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 27 kDa.

Target

  • Function
    Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
  • Tissue specificity
    In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes.
  • Sequence similarities
    Contains 1 C-type lectin domain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C type lectin domain family 9, member A antibody
    • C-type lectin domain family 9 member A antibody
    • CLC9A_HUMAN antibody
    • CLEC9A antibody
    • DNGR1 antibody
    • HEEE9341 antibody
    • PRO34046 antibody
    • UNQ9341 antibody
    see all

References

ab104909 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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