Overview

  • Product nameAnti-CLIC3 antibody
    See all CLIC3 primary antibodies
  • Description
    Chicken polyclonal to CLIC3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to amino acids 29-236 of Human CLIC3.

  • Positive control
    • human placenta

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab16050 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 25 kDa (predicted molecular weight: 26 kDa).

Target

  • RelevanceChloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
  • Cellular localizationNuclear, cytoplasmic and Single pass membrane. Predominantly nuclear but also found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain
  • Database links
  • Alternative names
    • 2300003G24Rik antibody
    • Chloride intracellular channel 3 antibody
    • Chloride intracellular channel protein 3 antibody
    • MGC109225 antibody
    • OTTHUMP00000022630 antibody
    see all

Anti-CLIC3 antibody images



  • Predicted band size : 26 kDa


    ab16050 staining human CLIC3 at 1/500 dilution in placenta extract by Western blot (Colorimetric signal development).

References for Anti-CLIC3 antibody (ab16050)

This product has been referenced in:
  • Kim TY  et al. Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res 66:7490-501 (2006). WB ; Human . Read more (PubMed: 16885346) »

See 1 Publication for this product

Product Wall

My apologies for the delay, I have just received the following information from the source of those two antibodies: -ab2634 Before loading samples had 5% (v/v) beta-mercaptoethanol was added and were boiled for 3 minutes. -ab16050 This antibody...

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