Overview

  • Product nameAnti-CLIC6 antibody
    See all CLIC6 primary antibodies
  • Description
    Rabbit polyclonal to CLIC6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 435-484 (RREDGEASEP RALGQEHDIT LFVKAGYDGE SIGNCPFSQR LFMILWLKGV) of Human CLIC6 (NP_444507).

  • Positive control
    • Jurkat cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab105786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 75 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport.
  • Tissue specificityExpressed in brain, placenta, pancreas and liver.
  • Sequence similaritiesBelongs to the chloride channel CLIC family.
    Contains 1 GST C-terminal domain.
  • DomainMembers of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localizationCytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Chloride channel form A antibody
    • Chloride intracellular channel 6 antibody
    • Chloride intracellular channel protein 6 antibody
    • CLIC1L antibody
    • Clic6 antibody
    • CLIC6_HUMAN antibody
    • Parchorin antibody
    see all

Anti-CLIC6 antibody images

  • Anti-CLIC6 antibody (ab105786) at 0.5 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 75 kDa

References for Anti-CLIC6 antibody (ab105786)

ab105786 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105786.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"