Anti-CLIC6 antibody - C-terminal (ab174236)

Overview

  • Product name
    Anti-CLIC6 antibody - C-terminal
    See all CLIC6 primary antibodies
  • Description
    Rabbit polyclonal to CLIC6 - C-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit
  • Immunogen

    Synthetic peptide within Human CLIC6 aa 676-704 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q96NY7

  • Positive control
    • 293 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab174236 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 73 kDa.

Target

  • Function
    May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport.
  • Tissue specificity
    Expressed in brain, placenta, pancreas and liver.
  • Sequence similarities
    Belongs to the chloride channel CLIC family.
    Contains 1 GST C-terminal domain.
  • Domain
    Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localization
    Cytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Chloride channel form A antibody
    • Chloride intracellular channel 6 antibody
    • Chloride intracellular channel protein 6 antibody
    • CLIC1L antibody
    • Clic6 antibody
    • CLIC6_HUMAN antibody
    • Parchorin antibody
    see all

Images

  • Anti-CLIC6 antibody - C-terminal (ab174236) at 1/100 dilution + 293 cell lysate at 35 µg

    Predicted band size : 73 kDa

References

ab174236 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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