Overview

  • Product name
  • Description
    Goat polyclonal to CLIP170
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Pig
  • Immunogen

    Synthetic peptide:

    C-PHSTHHGSRGEERP

    , corresponding to a region within C terminal amino acids 1393-1406 of Human CLIP170 (NP_002947.1, or amino acids 1358-1371 of NP_937883.1).

  • Positive control
    • Human prostate and thyroid tissues

Properties

Applications

Our Abpromise guarantee covers the use of ab115274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 162 kDa.
ELISA Use a concentration of 1 - 3 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Seems to be a intermediate filament associated protein that links endocytic vesicles to microtubules.
  • Tissue specificity
    Highly expressed in the Reed-Sternberg cells of Hodgkin disease.
  • Sequence similarities
    Contains 2 CAP-Gly domains.
  • Cellular localization
    Cytoplasm. Cytoplasm > cytoskeleton. Associated with the cytoskeleton. Localizes to the tips of microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAP GLY domain containing linker protein 1 antibody
    • CAP-Gly domain-containing linker protein 1 antibody
    • CLIP 170 antibody
    • CLIP antibody
    • CLIP-170 antibody
    • CLIP1 antibody
    • CLIP1_HUMAN antibody
    • CYLN1 antibody
    • cytoplasmic linker 1 antibody
    • Cytoplasmic linker protein 1 antibody
    • Cytoplasmic linker protein 170 alpha 2 antibody
    • Cytoplasmic linker protein 170 alpha-2 antibody
    • Cytoplasmic linker protein CLIP 170 antibody
    • Reed Steinberg cell expressed intermediate filament associated antibody
    • Reed Sternberg intermediate filament associated protein 3 antibody
    • Reed-Sternberg intermediate filament-associated protein antibody
    • Restin antibody
    • RSN antibody
    see all

Images

  • Staining of CLIP170 in Human prostate (formalin fixed, paraffin embedded) tissue, using ab115274 at 2.5 µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Staining of CLIP170 in Human thyroid (formalin fixed, paraffin embedded) tissue, using ab115274 at 2.5 µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab115274 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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