Overview

  • Product name
  • Description
    Rabbit polyclonal to CLK2
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment corresponding to Human CLK2 aa 3-66.
    Sequence:

    HPRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYH VRSRSSYDDRSSDR


    Database link: P49760

  • Positive control
    • Human colon tissue, RT-4 and U-251MG lysates, U-2OS cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab188141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
WB 1/100 - 1/250. Predicted molecular weight: 60 kDa.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylates on all three types of residues.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CDC like kinase 2 antibody
    • CDC-like kinase 2 antibody
    • CLK 2 antibody
    • CLK kinase antibody
    • CLK2 antibody
    • Clk2 Scamp3 antibody
    • CLK2_HUMAN antibody
    • Dual specificity protein kinase CLK2 antibody
    • hCLK 2 antibody
    • hCLK2 antibody
    • Tu52 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed paraffin embedded human colon tissue labeling CLK2 with ab188141 at 1/50 dilution

  • All lanes : Anti-CLK2 antibody (ab188141) at 1/100 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251MG cell lysate


    Predicted band size : 60 kDa
  • Immunocytochemical analysis of PFA/Triton X-100 fixed U-2OS cells labeling CLK2 with ab188141 at 1µg/ml

References

ab188141 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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