Overview

  • Product name
    Anti-CLNS1A antibody [2187C2a]
    See all CLNS1A primary antibodies
  • Description
    Mouse monoclonal [2187C2a] to CLNS1A
  • Tested applications
    Suitable for: Dot blot, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    CLNS1A recombinant fragment (Human), C terminal sequence.

Properties

Applications

Our Abpromise guarantee covers the use of ab53667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Dot blot Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 26 kDa.

Target

  • Function
    The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.
  • Sequence similarities
    Belongs to the pICln family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Nucleus. Cytoplasm > cytoskeleton. A small fraction is also associated with the cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • Chloride channel antibody
    • Chloride channel nucleotide sensitive 1A antibody
    • Chloride channel regulatory protein antibody
    • Chloride conductance regulator, volume sensitive antibody
    • Chloride conductance regulatory protein ICln antibody
    • Chloride ion current inducer protein antibody
    • ClCI antibody
    • CLNS 1A antibody
    • Clns1a antibody
    • CLNS1B antibody
    • I(Cln) antibody
    • ICln antibody
    • ICLN_HUMAN antibody
    • Methylosome subunit pICln antibody
    • nucleotide sensitive 1A antibody
    • Reticulocyte pICln antibody
    • Reticulocyte protein ICln antibody
    see all

Images

References

ab53667 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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