The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution.
RelevanceClostridia are a class of Firmicutes, including Clostridium and other similar genera. Clostridium is a genus of Gram-positive bacteria, that are obligate anaerobes capable of producing endospores. Clostridium includes common free-living bacteria as well as important pathogens.
Clostridium chauvoei is the causative agent of blackleg in cattle, it is a very virulent pathogen of cattle that causes fever, depression, lameness, and a high level of mortality.
Clostridium perfringens, which produces a huge array of invasins and exotoxins, causes wound and surgical infections that lead to gas gangrene, in addition to severe uterine infections. It is an important cause of food poisoning.
Clostridium sordellii is a rare bacterium that causes pneumonia, endocarditis, arthritis, peritonitis, and myonecrosis.
Clostridium novyi produces lethal toxins. It can cause malignant oedema (also known as false blackleg), necrotising fasciitis (commonly known as “flesh eating bacteria”) or myonecrosis. C. novyi (after removal of the toxin gene) has potential for use as an anti-tumour agent.
C. septicum can be a wound contaminant or can produce infection that rapidly progresses to sepsis. It is strongly associated with malignancy, particularly of the gastrointestinal and hematologic systems.
References for Anti-Clostridia spp antibody (FITC) (ab68501)
has not yet been referenced specifically in any publications.
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