Anti-Clostridium botulinum A Toxoid antibody [2A33] (ab82709)

Overview

  • Product nameAnti-Clostridium botulinum A Toxoid antibody [2A33]
    See all Clostridium botulinum A Toxoid primary antibodies
  • Description
    Mouse monoclonal [2A33] to Clostridium botulinum A Toxoid
  • Specificityab82709 reacts with Clostridium botulinum Toxin A heavy chain.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with Clostridium botulinum.
  • Immunogen

    Synthetic peptide:

    YIKNIINTSILN LRYESNH

    , corresponding to amino acid region 869-887 of Clostridium botulinum Toxin A.

Properties

Applications

Our Abpromise guarantee covers the use of ab82709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceClostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.
  • Alternative names
    • Atx antibody
    • BotA antibody
    • BOTOX antibody
    • Botulinum neurotoxin type A antibody
    • Botulism A toxoid antibody
    see all

References for Anti-Clostridium botulinum A Toxoid antibody [2A33] (ab82709)

ab82709 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Clostridium botulinum Purified protein (cell lysate)
Loading amount 5 µg
Specification cell lysate
Gel Running Conditions Reduced Denaturing (12%)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C
Username

Dr. chung sei kim

Verified customer

Submitted Jun 20 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"