Anti-Clostridium botulinum C Toxoid antibody (ab27165)

Overview

  • Product nameAnti-Clostridium botulinum C Toxoid antibody
  • Description
    Rabbit polyclonal to Clostridium botulinum C Toxoid
  • SpecificityThis antibody reacts with type C toxoid in an ELISA testing against toxoids A through F. Protection for both toxin type C and D in a mouse bioassay has been observed.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with
  • Immunogen

    Type C botulinum toxin treated with formaldehyde to avoid toxicity.

  • General notes


    Inhibitory activity in a mouse bioassay is specific for lethal doses of both type C and D toxin at a serum dilution of 1:100.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 15mM Sodium Azide.
    Constituents: Whole serum.
  • PurityWhole antiserum
  • Primary antibody notesInhibitory activity in a mouse bioassay is specific for lethal doses of both type C and D toxin at a serum dilution of 1:100.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab27165 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/8000.

In a toxoid ELISA with 1 µg toxoid/well the titre of this serum (specific absorbance values >1.5) is well above 8,000.

Target

  • RelevanceClostridium botulinum is a large anaerobic bacteria which causes the disease botulism. Seven different toxigenic types exist, each producing an immunologically distinct form of botulinum toxin, designated A,B,C1,D,E,F and G. These are neurotoxins that bind with high affinity to the peripheral neuronal presynaptic membrane. They hydrolyze SNAP 25, thereby blocking release of the neurotransmitter acetylcholine. This results in flaccid paralysis with frequent heart or respiratory failure.
  • Cellular localizationSecreted
  • Alternative names
    • BoNT/C1 antibody
    • Bontoxilysin C1 antibody
    • Botulinum neurotoxin C1 antibody
    • Botulinum neurotoxin type C1 nontoxic component antibody
    • Botulinum neurotoxin type C1 antibody
    • Botulism toxin C antibody
    • Clostridium botulinum toxin C antibody
    see all

References for Anti-Clostridium botulinum C Toxoid antibody (ab27165)

ab27165 has not yet been referenced specifically in any publications.

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Thank you very much for your enquiry. I'm very sorry for the delay in responding to you. Thank you for your patience. There is no problems in ordering 15- 20 units at a time for ab2029, ab20592, ab22037, ab22041, as these are quite small amounts...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"