Overview

  • Product name
  • Description
    Rabbit polyclonal to CLPP
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 48-232 of Human CLPP (Q16740).

  • Positive control
    • Human colon carcinoma tissue; Jurkat whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab126102 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 30 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
  • Tissue specificity
    Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney.
  • Sequence similarities
    Belongs to the peptidase S14 family.
  • Cellular localization
    Mitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATP dependent protease ClpAP (E coli) proteolytic subunit antibody
    • ATP dependent protease ClpAP proteolytic subunit antibody
    • ATP dependent protease ClpAP proteolytic subunit human antibody
    • ATP dependent proteolytic subunit homolog (E coli) antibody
    • ATP dependent proteolytic subunit homolog antibody
    • Caseinolytic peptidase ATP dependent proteolytic subunit homolog antibody
    • Caseinolytic protease ATP dependent proteolytic subunit E coli antibody
    • clpP antibody
    • ClpP caseinolytic peptidase ATP dependent proteolytic subunit antibody
    • ClpP caseinolytic peptidase ATP dependent proteolytic subunit homolog antibody
    • CLPP_HUMAN antibody
    • Endopeptidase Clp antibody
    • mitochondrial antibody
    • Putative ATP dependent Clp protease proteolytic subunit mitochondrial antibody
    • Putative ATP dependent Clp protease proteolytic subunit antibody
    • Putative ATP-dependent Clp protease proteolytic subunit antibody
    see all

Images

  • Anti-CLPP antibody (ab126102) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

    Predicted band size : 30 kDa
  • ab126102, at 1/250 dilution, staining CLPP in paraffin-embedded Human colon carcinoma tissue by Immunohistochemistry.

References

ab126102 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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