Anti-CLVS2 antibody - C-terminal (ab170210)

Overview

  • Product name
    Anti-CLVS2 antibody - C-terminal
    See all CLVS2 primary antibodies
  • Description
    Rabbit polyclonal to CLVS2 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human CLVS2 aa 258-287 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q5SYC1

  • Positive control
    • Mouse liver tissue lysate; Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab170210 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 38 kDa.

Target

  • Function
    Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
  • Sequence similarities
    Contains 1 CRAL-TRIO domain.
  • Domain
    The CRAL-TRIO domain is required for targeting to the membrane and for binding PtdIns(3,5)P2.
  • Cellular localization
    Golgi apparatus > trans-Golgi network membrane. Cytoplasmic vesicle > clathrin-coated vesicle. Early endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA160A10.4 antibody
    • C6orf212 antibody
    • C6orf213 antibody
    • Clavesin-2 antibody
    • clvs2 antibody
    • CLVS2_HUMAN antibody
    • Retinaldehyde-binding protein 1-like 2 antibody
    • RLBP1L2 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling CLVS2 with ab170210 at 1/10 dilution, followed by peroxidase conjugated secondary antibody and DAB staining.

  • Anti-CLVS2 antibody - C-terminal (ab170210) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size: 38 kDa

References

ab170210 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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