Overview

  • Product nameAnti-CMAS antibody
    See all CMAS primary antibodies
  • Description
    Mouse monoclonal to CMAS
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: EGYDSVFSVV RRHQFRWSEI QKGVREVTEP LNLNPAKRPR RQDWDGELYE NGSFYFAKRH LIEMGYLQGG KMAYYEMRAE HSVDIDVDID WPIAEQRVLR , corresponding to amino acids 164-264 of Human CMAS

Properties

Applications

Our Abpromise guarantee covers the use of ab57454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCatalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
    • Tissue specificityUbiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen.
    • PathwayAmino-sugar metabolism; N-acetylneuraminate metabolism.
    • Sequence similaritiesBelongs to the CMP-NeuNAc synthase family.
    • DomainThe BC2 (basic cluster 2) motif is necessary and sufficient for the nuclear localization and contains the catalytic active site. The localization in the nucleus is however not required for the enzyme activity.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • CMAS antibody
      • CMP N acetylneuraminic acid synthase antibody
      • CMP Neu5Ac synthetase antibody
      • CMP NeuNAc synthetase antibody
      • CMP sialic acid synthetase antibody
      • CMP-N-acetylneuraminic acid synthase antibody
      • CMP-N-acetylneuraminic acid synthetase antibody
      • CMP-NeuNAc synthase antibody
      • CSS antibody
      • Cytidine 5' monophosphate N acetylneuraminic acid synthetase antibody
      • Cytidine 5-prime-monophosphate N-acetylneuraminic acid synthetase antibody
      • Cytidine monophosphate N acetylneuraminic acid synthetase antibody
      • N acylneuraminate cytidylyltransferase antibody
      • N-acylneuraminate cytidylyltransferase antibody
      • NEUA_HUMAN antibody
      see all

    Anti-CMAS antibody images

    • CMAS antibody (ab57454) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human salivary gland.


    • Predicted band size : 48 kDa
      CMAS antibody (ab57454) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-CMAS antibody (ab57454)

    ab57454 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57454.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"