Overview

  • Product name
  • Description
    Rabbit polyclonal to CMAS
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 69-384 of Human CMAS (NP_061156)

  • Positive control
    • 293T and HeLaS3 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab97655 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.
ICC/IF 1/100 - 1/200.

Target

  • Function
    Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
  • Tissue specificity
    Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen.
  • Pathway
    Amino-sugar metabolism; N-acetylneuraminate metabolism.
  • Sequence similarities
    Belongs to the CMP-NeuNAc synthase family.
  • Domain
    The BC2 (basic cluster 2) motif is necessary and sufficient for the nuclear localization and contains the catalytic active site. The localization in the nucleus is however not required for the enzyme activity.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CMAS antibody
    • CMP N acetylneuraminic acid synthase antibody
    • CMP Neu5Ac synthetase antibody
    • CMP NeuNAc synthetase antibody
    • CMP sialic acid synthetase antibody
    • CMP-N-acetylneuraminic acid synthase antibody
    • CMP-N-acetylneuraminic acid synthetase antibody
    • CMP-NeuNAc synthase antibody
    • CSS antibody
    • Cytidine 5' monophosphate N acetylneuraminic acid synthetase antibody
    • Cytidine 5-prime-monophosphate N-acetylneuraminic acid synthetase antibody
    • Cytidine monophosphate N acetylneuraminic acid synthetase antibody
    • N acylneuraminate cytidylyltransferase antibody
    • N-acylneuraminate cytidylyltransferase antibody
    • NEUA_HUMAN antibody
    see all

Images

  • All lanes : Anti-CMAS antibody (ab97655) at 1/1500 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : HeLaS3 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CMAS antibody (ab97655) at 1/200 dilution. Lower panel is merged with DNA probe.

References

ab97655 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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