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Rabbit polyclonal to CMAS
Predicted to work with:
Mouse, Rat, Cow
Recombinant fragment, corresponding to a region within amino acids 69-384 of Human CMAS (NP_061156)
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 48 kDa.
1/100 - 1/200.
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen.
Amino-sugar metabolism; N-acetylneuraminate metabolism.
Belongs to the CMP-NeuNAc synthase family.
The BC2 (basic cluster 2) motif is necessary and sufficient for the nuclear localization and contains the catalytic active site. The localization in the nucleus is however not required for the enzyme activity.
Information by UniProt
CMP N acetylneuraminic acid synthase antibody
CMP Neu5Ac synthetase antibody
Western blot - Anti-CMAS antibody (ab97655)
All lanes : Anti-CMAS antibody (ab97655) at 1/1500 dilution Lane 1 : 293T whole cell lysate Lane 2 : HeLaS3 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size: 48 kDa 7.5% SDS PAGE
Immunocytochemistry/ Immunofluorescence - Anti-CMAS antibody (ab97655)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CMAS antibody (ab97655) at 1/200 dilution. Lower panel is merged with DNA probe.
has not yet been referenced specifically in any publications.
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