Overview

  • Product nameAnti-CMPK2 antibody
    See all CMPK2 primary antibodies
  • Description
    Rabbit polyclonal to CMPK2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 150-180 of Human CMPK2.

  • Positive control
    • Hela cell line lysates; Human prostate carcinoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab103658 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG

Associated products

Applications

Our Abpromise guarantee covers the use of ab103658 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 49 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMay participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.
  • Tissue specificityAmong all investigated tumors, leukemia cells show the most abundant expression.
  • Sequence similaritiesBelongs to the thymidylate kinase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1200004E04Rik antibody
    • Cmpk2 antibody
    • CMPK2_HUMAN antibody
    • Cytidine monophosphate (UMP CMP) kinase 2, mitochondrial antibody
    • mitochondrial antibody
    • Mitochondrial UMP CMP kinase antibody
    • OTTHUMP00000200305 antibody
    • Thymidine monophosphate kinase 2 antibody
    • TMPK2 antibody
    • TYKi antibody
    • UMP CMP kinase 2, mitochondrial antibody
    • UMP CMP kinase 2, mitochondrial; cytidylate kinase 2 antibody
    • UMP CMPK2 antibody
    • UMP-CMP kinase 2 antibody
    see all

Anti-CMPK2 antibody images

  • Anti-CMPK2 antibody (ab103658) at 1/100 dilution + Hela cell line lysates at 35 µg

    Predicted band size : 49 kDa
  • ab103658 at 1/50 dilution, staining CMPK2 in Human prostate carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

References for Anti-CMPK2 antibody (ab103658)

ab103658 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"