Overview

  • Product name
  • Description
    Rabbit polyclonal to CMT
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 180-229 (TAGSNFNHVV QNEKSDTHTL VTSGVYAWFR HPSYVGWFYW SIGTQVMLCN) of human CMT (NP_036537)

  • Positive control
    • Fetal heart lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab80872 is purified by a peptide affinity chromatography method.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab80872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/1562500.

Target

  • Function
    Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
  • Tissue specificity
    Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons.
  • Sequence similarities
    Belongs to the isoprenylcysteine O-methyltransferase family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1700008E11Rik antibody
    • C80758 antibody
    • fcmt antibody
    • Gm13095 antibody
    • HSTE14 antibody
    • Icmt antibody
    • ICMT_HUMAN antibody
    • Isoprenylcysteine carboxylmethyltransferase antibody
    • MGC118506 antibody
    • MGC39955 antibody
    • MGC95322 antibody
    • MST098 antibody
    • MSTP098 antibody
    • OTTMUSG00000010406 antibody
    • pcCMT antibody
    • PCMT antibody
    • PPMT antibody
    • Prenylated protein carboxyl methyltransferase antibody
    • Prenylcysteine carboxyl methyltransferase antibody
    • Protein-S-isoprenylcysteine O-methyltransferase antibody
    • RP23-421E12.4 antibody
    • STE14 antibody
    see all

Anti-CMT antibody images

  • Anti-CMT antibody (ab80872) at 1 µg/ml + fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 32 kDa
    Observed band size : 32 kDa

References for Anti-CMT antibody (ab80872)

ab80872 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab80872.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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