Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab48066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • CCHC type zinc finger nucleic acid binding protein
    • Cellular nucleic acid binding protein
    • Cellular nucleic acid-binding protein
    • CNBP
    • CNBP_HUMAN
    • CNBP1
    • DM2
    • Erythroid differentiation related
    • PROMM
    • Proximal myotonic myopathy nucleic acid binding protein
    • RNF163
    • Sterol regulatory element binding protein
    • ZCCHC22
    • Zinc finger protein 273
    • Zinc finger protein 9
    • Zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
    • ZNF9
    see all
  • FunctionSingle stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.
  • Tissue specificityPresent in all tissues examined.
  • Involvement in diseaseDefects in CNBP are the cause of dystrophia myotonica type 2 (DM2) [MIM:602668]; also known as proximal myotonic myopathy (PROMM). A multisystem disease characterized by the association of proximal muscle weakness with myotonia, cardiac manifestations and cataract. Additional features can include hyperhidrosis, testicular atrophy, insulin resistance and diabetes and central nervous system anomalies in rare cases. Note=The causative mutation is a CCTG expansion (mean approximately 5000 repeats) located in intron 1 of the CNBP gene.
  • Sequence similaritiesContains 7 CCHC-type zinc fingers.
  • Cellular localizationCytoplasm. Endoplasmic reticulum.
  • Information by UniProt

References for CNBP peptide (ab48066)

ab48066 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"